|Full Name||Claire Redfield|
|First Appearance||Resident Evil 2|
|Latest Appearance||Resident Evil: The Darkside Chronicles|
|Portrayed by|| Alyson Court [English]
Yūko Kaida [Japanese]
Resident Evil 2 Edit
Two months and five days after the events at the mansion, the t-virus is released in the sewer system of Raccoon City, infecting rats. The rats spread the virus throughout the whole of Raccoon City, whether it be animals or humans. When Claire is almost eaten alive by a virus carrier, she is saved by a rookie cop, Leon S. Kennedy. Claire and Leon agree that they have to get out out of Raccoon City as soon as possible, and hatch a plan. The two get separated and Claire explores the deserted police station, and then encounters the corrupt Chief Irons and twelve-year-old Sherry Birkin, who is the daughter of two important Umbrella researchers, Anette and William Birkin. Claire encountered Annette on at least one occasion, during which she accused Claire of being a spy for Umbrella. Sherry and Claire try finding a way out of the city, being stalked by a mutated Birkin. When inside the sewers, Sherry and Claire were separated. During this time, Sherry was found by Birkin and infected with the G-virus. Upon their reunion, Claire tries finding a cure for Sherry in Umbrella's underground laboratory. While in the laboratory, Claire runs into Annette one more time, before William arrives and fatally wounds his former wife. Before dying, Annette gives Claire the instructions for creating the G-virus antidote, making her escape and having Leon take Sherry to an escape train before the lab self destructed. Claire's escape is thwarted by Birkin, and she is forced to fight the monster and incapacitate it. Claire then rushes to the train and successfully gives Sherry the vaccine. But Birkin, still not down, attacks the train and launches another self-destruct sequence. Claire, Leon, and Sherry escape moments before the train explodes, destroying Birkin completely. After this, Leon urges Claire to leave them and search for her brother.